{"id":34196,"date":"2024-01-13T08:41:15","date_gmt":"2024-01-13T08:41:15","guid":{"rendered":"https:\/\/www.greatassignmenthelp.com\/questions\/?p=34196"},"modified":"2024-01-13T08:41:15","modified_gmt":"2024-01-13T08:41:15","slug":"what-is-the-role-of-dna-ligase-in-the-elongation-of-the-lagging-strand-during-dna-replication","status":"publish","type":"post","link":"https:\/\/www.greatassignmenthelp.com\/questions\/what-is-the-role-of-dna-ligase-in-the-elongation-of-the-lagging-strand-during-dna-replication\/","title":{"rendered":"What is the role of DNA ligase in the elongation of the lagging strand during DNA replication?"},"content":{"rendered":"

Question:-<\/strong> What is the role of DNA ligase in the elongation of the lagging strand during DNA replication?<\/p>\n

Select one:<\/p>\n

1:- It is involved in the lengthening of telomeres<\/p>\n

2:- It adds nucleotides to the leading strand<\/p>\n

3:- It unwinds the DNA double helix.<\/p>\n

4:- It joins Okazaki fragments together<\/p>\n

5:- It synthesizes RNA nucleotides to make a primer<\/p>\n

 <\/p>\n

Answer:-\u00a0 4. It joins Okazaki fragments together<\/strong><\/p>\n

DNA ligase is involved in lagging strand elongation and the role it plays involves joining together blocks known as Okazaki fragments, which are synthesized short stretches in 3\u2019 to 5\u2019.<\/p>\n

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As the DNA polymerase synthesizes these fragments, there is space between each fragment. DNA ligase seals these gaps by enzymatically polymerizing phosphodiester bonds between the 3\u2019 hydroxy end of one Okazaki fragment and the 5\u2032 phosphate end of another. This combines the fragments into a continuous thread.<\/p>\n

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The other options do not describe the role of DNA ligase:<\/p>\n